Journal Articles
Chivers JM, Whiles SA, Miles CB, Biederman BE, Ellison MF, Lovingood CW, Wright MH, Hoover DB, Raafey MA, Youngberg GA, Venkatachalam MA, Zheleznova NN, Yang C, Liu P, Kriegel AJ, Cowley AW, O'Connor PM, Picken MM, Polichnowski AJ. Brown-Norway chromosome 1 mitigates the upregulation of proinflammatory pathways in mTAL cells and subsequent age-related CKD in Dahl SS/JrHsdMcwi rats. Am J Physiol Renal Physiol. 2023 Feb 1;324(2):F193-F210. doi:10.1152/ajprenal.00145.2022. Epub 2022 Dec 8. PMID: 36475869; PMCID: PMC9886360.
Jensen DM, Han P, Mangala LS, Lopez-Berestein G, Sood AK, Liu J, Kriegel AJ, Usa K, Widlansky ME, Liang M. Broad-acting therapeutic effects of miR-29b-chitosan on hypertension and diabetic complications. Mol Ther. 2022 Nov 2;30(11):3462-3476. doi: 10.1016/j.ymthe.2022.08.007. Epub 2022 Aug 13. PMID:35965413; PMCID: PMC9637778.
Mukherjee D, Rana U, Kriegel AJ, Liu P, Michalkiewicz T, Konduri GG. Fetal pulmonary hypertension: dysregulated microRNA-34c-Notch1 axis contributes to impaired angiogenesis in an ovine model. Pediatr Res. 2022 Jun 18:10.1038/s41390-022-02151-3. doi: 10.1038/s41390-022-02151-3. Epub ahead of print. PMID: 35717485; PMCID: PMC9759620.
Ilatovskaya DV, Levchenko V, Winsor K, Blass GR, Spires DR, Sarsenova E, Polina I, Zietara A, Paterson M, Kriegel AJ, Staruschenko A. Effects of elevation of ANP and its deficiency on cardiorenal function. JCI Insight. 2022 May 9;7(9):e148682. doi: 10.1172/jci.insight.148682. PMID: 35380994; PMCID:PMC9090260.
Adam RJ, Williams AC, Kriegel AJ. Comparison of the surgical resection and infarct 5/6 nephrectomy rat models of chronic kidney disease. Am J Physiol Renal Physiol. 2022 Jun 1;322(6):F639-F654. doi: 10.1152/ajprenal.00398.2021. Epub 2022 Apr 4. PMID: 35379002; PMCID: PMC9076416.
Patil CN, Ritter ML, Wackman KK, Oliveira V, Balapattabi K, Grobe CC, Brozoski DT, Reho JJ, Nakagawa P, Mouradian GC Jr, Kriegel AJ, Kwitek AE, Hodges MR, Segar JL, Sigmund CD, Grobe JL. Cardiometabolic effects of DOCA-salt in male C57BL/6J mice are variably dependent on sodium and nonsodium components of diet. Am J Physiol Regul Integr Comp Physiol. 2022 Jun 1;322(6):R467-R485. doi:
10.1152/ajpregu.00017.2022. Epub 2022 Mar 29. PMID: 35348007; PMCID: PMC9054347.
Park J, Foox J, Hether T, Danko DC, Warren S, Kim Y, Reeves J, Butler DJ, Mozsary C, Rosiene J, Shaiber A, Afshin EE, MacKay M, Rendeiro AF, Bram Y, Chandar V, Geiger H, Craney A, Velu P, Melnick AM, Hajirasouliha I, Beheshti A, Taylor D, Saravia-Butler A, Singh U, Wurtele ES, Schisler J, Fennessey S,
Corvelo A, Zody MC, Germer S, Salvatore S, Levy S, Wu S, Tatonetti NP, Shapira S, Salvatore M, Westblade LF, Cushing M, Rennert H, Kriegel AJ, Elemento O, Imielinski M, Rice CM, Borczuk AC, Meydan C, Schwartz RE, Mason CE. System-wide transcriptome damage and tissue identity loss in COVID-19 patients. Cell Rep Med. 2022 Jan 24;3(2):100522. doi: 10.1016/j.xcrm.2022.100522. PMID: 35233546; PMCID: PMC8784611.
Gohar EY, De Miguel C, Obi IE, Daugherty EM, Hyndman KA, Becker BK, Jin C, Sedaka R, Johnston JG, Liu P, Speed JS, Mitchell T, Kriegel AJ, Pollock JS, Pollock DM. Acclimation to a High-Salt Diet Is Sex Dependent. J Am Heart Assoc. 2022 Mar;11(5):e020450. doi: 10.1161/JAHA.120.020450. Epub 2022 Feb 22. PMID:35191321; PMCID: PMC9075092.
Moore KJM, Cahill J, Aidelberg G, Aronoff R, Bektaş A, Bezdan D, Butler DJ, Chittur SV, Codyre M, Federici F, Tanner NA, Tighe SW, True R, Ware SB, Wyllie AL, Afshin EE, Bendesky A, Chang CB, Dela Rosa R 2nd, Elhaik E, Erickson D, Goldsborough AS, Grills G, Hadasch K, Hayden A, Her SY, Karl JA, Kim CH, Kriegel AJ, Kunstman T, Landau Z, Land K, Langhorst BW, Lindner AB, Mayer BE, McLaughlin LA, McLaughlin MT, Molloy J, Mozsary C, Nadler JL, D'Silva M, Ng D, O'Connor DH, Ongerth JE, Osuolale O, Pinharanda A, Plenker D, Ranjan R, Rosbash M, Rotem A, Segarra J, Schürer S, Sherrill-Mix S, Solo-Gabriele H, To S, Vogt MC, Yu AD, Mason CE; gLAMP Consortium. Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications. J Biomol Tech. 2021 Sep;32(3):228-275. doi: 10.7171/jbt.21-3203-017. PMID: 35136384; PMCID: PMC8802757.
Adam RJ, Paterson MR, Wardecke L, Hoffmann BR, Kriegel AJ. Functionally Essential Tubular Proteins Are Lost to Urine-Excreted, Large Extracellular Vesicles during Chronic Renal Insufficiency. Kidney360. 2020 Oct;1(10):1105-1115. doi: 10.34067/kid.0001212020. Epub 2020 Oct 29. PMID: 34263177; PMCID: PMC8276873.
Spires DR, Palygin O, Levchenko V, Isaeva E, Klemens CA, Khedr S,Nikolaienko O, Kriegel A, Cheng X, Yeo JY, Joe B, Staruschenko A. Sexual dimorphism in the progression of type 2 diabetic kidney disease in T2DN rats. Physiol Genomics. 2021 Jun 1;53(6):223-234. doi: 10.1152/physiolgenomics.00009.2021. Epub 2021 Apr 19. PMID: 33870721; PMCID:PMC8285576.
Klemens CA, Chulkov EG, Wu J, Hye Khan MA, Levchenko V, Flister MJ, Imig JD, Kriegel AJ, Palygin O, Staruschenko A. Loss of Chloride Channel 6 (CLC-6) Affects Vascular Smooth Muscle Contractility and Arterial Stiffness via Alterations to Golgi Calcium Stores. Hypertension. 2021 Feb;77(2):582-593. doi:
10.1161/HYPERTENSIONAHA.120.16589. Epub 2021 Jan 4. PMID: 33390052; PMCID:PMC7856014.
Park J, Foox J, Hether T, Danko D, Warren S, Kim Y, Reeves J, Butler DJ, Mozsary C, Rosiene J, Shaiber A, Afshinnekoo E, MacKay M, Bram Y, Chandar V, Geiger H, Craney A, Velu P, Melnick AM, Hajirasouliha I, Beheshti A, Taylor D, Saravia-Butler A, Singh U, Wurtele ES, Schisler J, Fennessey S, Corvelo A, Zody
MC, Germer S, Salvatore S, Levy S, Wu S, Tatonetti N, Shapira S, Salvatore M, Loda M, Westblade LF, Cushing M, Rennert H, Kriegel AJ, Elemento O, Imielinski M, Borczuk AC, Meydan C, Schwartz RE, Mason CE. Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps. bioRxiv [Preprint]. 2021 Mar 9:2021.03.08.434433. doi: 10.1101/2021.03.08.434433. PMID: 33758858; PMCID: PMC7987017.
MacKay MJ, Hooker AC, Afshinnekoo E, Salit M, Kelly J, Feldstein JV, Haft N, Schenkel D, Nambi S, Cai Y, Zhang F, Church G, Dai J, Wang CL, Levy S, Huber J, Ji HP, Kriegel A, Wyllie AL, Mason CE. The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing. Nat Biotechnol. 2020 Sep;38(9):1021-1024. doi: 10.1038/s41587-020-0655-4. PMID: 32820257; PMCID: PMC7543743.
Paterson MR, Geurts AM, Kriegel AJ. miR-146b-5p has a sex-specific role in renal and cardiac pathology in a rat model of chronic kidney disease. Kidney Int. 2019 Dec;96(6):1332-1345. doi: 10.1016/j.kint.2019.07.017. Epub 2019 Aug 16. PMID: 31668631; PMCID: PMC6941490.
Abais-Battad JM, Alsheikh AJ, Pan X, Fehrenbach DJ, Dasinger JH, Lund H, Roberts ML, Kriegel AJ, Cowley AW Jr, Kidambi S, Kotchen TA, Liu P, Liang M, Mattson DL. Dietary Effects on Dahl Salt-Sensitive Hypertension, Renal Damage, and the T Lymphocyte Transcriptome. Hypertension. 2019 Oct;74(4):854-863. doi:10.1161/HYPERTENSIONAHA.119.12927. Epub 2019 Sep 3. PMID: 31476910; PMCID:PMC6739138.
Hader SN, Zinkevich N, Norwood Toro LE, Kriegel AJ, Kong A, Freed JK, Gutterman DD, Beyer AM. Detrimental effects of chemotherapy on human coronary microvascular function. Am J Physiol Heart Circ Physiol. 2019 Oct 1;317(4):H705-H710. doi: 10.1152/ajpheart.00370.2019. Epub 2019 Aug 9. PMID:31397169; PMCID: PMC6843017.
Lai PY, Jing X, Michalkiewicz T, Entringer B, Ke X, Majnik A, Kriegel AJ, Liu P, Lane RH, Konduri GG. Adverse early-life environment impairs postnatal lung development in mice. Physiol Genomics. 2019 Sep 1;51(9):462-470. doi:10.1152/physiolgenomics.00016.2019. Epub 2019 Aug 2. PMID: 31373541; PMCID: PMC6766700.
Liu Y, Kriegel AJ, Liang M. Library Preparation for Multiplexed Reduced Representation Bisulfite Sequencing with a Universal Adapter. Methods Mol Biol. 2019;2018:177-194. doi: 10.1007/978-1-4939-9581-3_8. PMID: 31228157.
Ilatovskaya DV, Levchenko V, Pavlov TS, Isaeva E, Klemens CA, Johnson J, Liu P, Kriegel AJ, Staruschenko A. Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC). EBioMedicine. 2019 Feb;40:663-674. doi: 10.1016/j.ebiom.2019.01.006. Epub 2019 Feb 8. PMID: 30745171; PMCID:PMC6413684.
Nasci VL, Chuppa S, Griswold L, Goodreau KA, Dash RK, Kriegel AJ. miR-21-5p regulates mitochondrial respiration and lipid content in H9C2 cells. Am JPhysiol Heart Circ Physiol. 2019 Mar 1;316(3):H710-H721. doi: 10.1152/ajpheart.00538.2017. Epub 2019 Jan 18. PMID: 30657727; PMCID:PMC6459316.
Baker MA, Wang F, Liu Y, Kriegel AJ, Geurts AM, Usa K, Xue H, Wang D, Kong Y, Liang M. MiR-192-5p in the Kidney Protects Against the Development of Hypertension. Hypertension. 2019 Feb;73(2):399-406. doi:10.1161/HYPERTENSIONAHA.118.11875. PMID: 30595117; PMCID: PMC6339564.
Kriegel AJ, Terhune SS, Greene AS, Noon KR, Pereckas MS, Liang M. Isomer-specific effect of microRNA miR-29b on nuclear morphology. J Biol Chem. 2018 Sep 7;293(36):14080-14088. doi: 10.1074/jbc.RA117.001705. Epub 2018 Jul 13. PMID:30006350; PMCID: PMC6130969.
Miller JJ, Aoki K, Mascari CA, Beltrame AK, Sokumbi O, North PE, Tiemeyer M, Kriegel AJ, Dahms NM. α-Galactosidase A-deficient rats accumulate glycosphingolipids and develop cardiorenal phenotypes of Fabry disease. FASEB J. 2019 Jan;33(1):418-429. doi: 10.1096/fj.201800771R. Epub 2018 Jul 6. PMID:
29979634; PMCID: PMC6629127.
Widlansky ME, Jensen DM, Wang J, Liu Y, Geurts AM, Kriegel AJ, Liu P, Ying R, Zhang G, Casati M, Chu C, Malik M, Branum A, Tanner MJ, Tyagi S, Usa K, Liang M. miR-29 contributes to normal endothelial function and can restore it in cardiometabolic disorders. EMBO Mol Med. 2018 Mar;10(3):e8046. doi:
10.15252/emmm.201708046. PMID: 29374012; PMCID: PMC5840545.
Chuppa S, Liang M, Liu P, Liu Y, Casati MC, Cowley AW, Patullo L, Kriegel AJ. MicroRNA-21 regulates peroxisome proliferator-activated receptor alpha, a molecular mechanism of cardiac pathology in Cardiorenal Syndrome Type 4. Kidney Int. 2018 Feb;93(2):375-389. doi: 10.1016/j.kint.2017.05.014. Epub 2017 Jul 29. PMID: 28760335; PMCID: PMC5787401.
Paterson MR, Kriegel AJ. MiR-146a/b: a family with shared seeds and different roots. Physiol Genomics. 2017 Apr 1;49(4):243-252. doi:10.1152/physiolgenomics.00133.2016. Epub 2017 Feb 17. PMID: 28213571; PMCID:PMC5407182.
Usa KS, Liu Y, Kurth T, Kriegel AJ, Mattson DL, Cowley AW Jr, Liang M. Renal Delivery of Anti-microRNA Oligonucleotides in Rats. Methods Mol Biol. 2017;1527:409-419. doi: 10.1007/978-1-4939-6625-7_31. PMID: 28116733.
Kriegel AJ, Gartz M, Afzal MZ, de Lange WJ, Ralphe JC, Strande JL. Molecular Approaches in HFpEF: MicroRNAs and iPSC-Derived Cardiomyocytes. J Cardiovasc Transl Res. 2017 Jun;10(3):295-304. doi: 10.1007/s12265-016-9723-z. Epub 2016 Dec 28. PMID: 28032312; PMCID: PMC5937699.
Kriegel AJ, Baker MA, Liu Y, Liu P, Cowley AW Jr, Liang M. Endogenous microRNAs in human microvascular endothelial cells regulate mRNAs encoded by hypertension-related genes. Hypertension. 2015 Oct;66(4):793-9. doi:10.1161/HYPERTENSIONAHA.115.05645. Epub 2015 Aug 17. PMID: 26283043; PMCID: PMC4567475.
Olson JM, Yan Y, Bai X, Ge ZD, Liang M, Kriegel AJ, Twaroski DM, Bosnjak ZJ. Up-regulation of microRNA-21 mediates isoflurane-induced protection of cardiomyocytes. Anesthesiology. 2015 Apr;122(4):795-805. doi: 10.1097/ALN.0000000000000567. PMID: 25536091; PMCID: PMC4366274.
Xu X, Kriegel AJ, Jiao X, Liu H, Bai X, Olson J, Liang M, Ding X. miR-21 in ischemia/reperfusion injury: a double-edged sword? Physiol Genomics. 2014 Nov 1;46(21):789-97. doi: 10.1152/physiolgenomics.00020.2014. Epub 2014 Aug 26. PMID: 25159851; PMCID: PMC4280148.
Kriegel AJ, Liang M. MicroRNA in situ hybridization for formalin fixed kidney tissues. J Vis Exp. 2013 Nov 30;(81):50785. doi: 10.3791/50785. PMID:24326287; PMCID: PMC3992125.
Kriegel AJ, Liu Y, Liu P, Baker MA, Hodges MR, Hua X, Liang M.
Characteristics of microRNAs enriched in specific cell types and primary tissue types in solid organs. Physiol Genomics. 2013 Dec 1;45(23):1144-56. doi: 10.1152/physiolgenomics.00090.2013. Epub 2013 Oct 1. PMID: 24085797; PMCID: PMC3882707.
Jia P, Teng J, Zou J, Fang Y, Jiang S, Yu X, Kriegel AJ, Liang M, Ding X. Intermittent exposure to xenon protects against gentamicin-induced nephrotoxicity. PLoS One. 2013 May 30;8(5):e64329. doi: 10.1371/journal.pone.0064329. PMID: 23737979; PMCID: PMC3667819.
Yu X, Lu C, Liu H, Rao S, Cai J, Liu S, Kriegel AJ, Greene AS, Liang M, Ding X. Hypoxic preconditioning with cobalt of bone marrow mesenchymal stem cells improves cell migration and enhances therapy for treatment of ischemic acute kidney injury. PLoS One. 2013 May 9;8(5):e62703. doi: 10.1371/journal.pone.0062703. PMID: 23671625; PMCID: PMC3650042.
Fang Y, Yu X, Liu Y, Kriegel AJ, Heng Y, Xu X, Liang M, Ding X. miR-29c is downregulated in renal interstitial fibrosis in humans and rats and restored by HIF-α activation. Am J Physiol Renal Physiol. 2013 May 15;304(10):F1274-82. doi: 10.1152/ajprenal.00287.2012. Epub 2013 Mar 6. PMID: 23467423; PMCID: PMC3651624.
Xu X, Kriegel AJ, Liu Y, Usa K, Mladinov D, Liu H, Fang Y, Ding X, Liang M. Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21. Kidney Int. 2012 Dec;82(11):1167-75. doi: 10.1038/ki.2012.241. Epub 2012 Jul 11. PMID: 22785173; PMCID: PMC3777822.
Kriegel AJ, Didier DN, Li P, Lazar J, Greene AS. Mechanisms of cardioprotection resulting from Brown Norway chromosome 16 substitution in the salt-sensitive Dahl rat. Physiol Genomics. 2012 Aug 17;44(16):819-27. doi: 10.1152/physiolgenomics.00175.2011. Epub 2012 Jul 3. PMID: 22759922; PMCID:PMC3774569.
Kriegel AJ, Mladinov D, Liang M. Translational study of microRNAs and its application in kidney disease and hypertension research. Clin Sci (Lond). 2012 May 1;122(10):439-47. doi: 10.1042/CS20110159. PMID: 22283365; PMCID: PMC4428581.
Kriegel AJ, Liu Y, Fang Y, Ding X, Liang M. The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injury. Physiol Genomics. 2012 Feb 27;44(4):237-44. doi: 10.1152/physiolgenomics.00141.2011. Epub 2012 Jan 3. PMID: 22214600; PMCID: PMC3289120.
Kriegel AJ, Liu Y, Cohen B, Usa K, Liu Y, Liang M. MiR-382 targeting of kallikrein 5 contributes to renal inner medullary interstitial fibrosis. Physiol Genomics. 2012 Feb 27;44(4):259-67. doi: 10.1152/physiolgenomics.00173.2011. Epub 2011 Dec 27. PMID: 22202692; PMCID: PMC3289118.
Kriegel AJ, Fang Y, Liu Y, Tian Z, Mladinov D, Matus IR, Ding X, Greene AS, Liang M. MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor beta 1: a novel role of miR-382. Nucleic Acids Res. 2010 Dec;38(22):8338-47. doi: 10.1093/nar/gkq718. Epub 2010 Aug 16. PMID:20716515; PMCID: PMC3001085.
de Resende MM, Kriegel AJ, Greene AS. Combined effects of low-dose spironolactone and captopril therapy in a rat model of genetic hypertrophic cardiomyopathy. J Cardiovasc Pharmacol. 2006 Dec;48(6):265-73. doi:10.1097/01.fjc.0000248236.43760.86. PMID: 17204904.
Book Entries/Chapters
Yong Liu, Alison J. Kriegel, Mingyu Liang. (2019). Library Preparation for Multiplexed Reduced Representation Bisulfite Sequencing with a Universal Adapter. Methylation and Epigenetics in Rat, Methods Mol Biol. 177‐194.
Kristie S. Usa, Yong Liu, Terry Kurth, Alison J. Kriegel, David L. Mattson, Allen W. Cowley Jr., and Mingyu Liang. (2017). Renal Delivery of Anti‐microRNA Oligonucleotides in Rats. Hypertension: Methods and Protocols, (Methods Mol Biol.), 1527:409‐419.