Ongoing work is focused on identifying mechanisms regulating changes in cardiomyocyte metabolism observed in CKD models.
Cardiomyocyte Metabolism in CKD
Cardiovasular Changes in CKD
Dramatic vasular changes occur during CKD pathology. We are focused on understanding how these vascular changes contribute to multi-system CKD pathology.
Effects of CKD on CV Function During Growth
Pediatric CKD results in numerous complications including impaired growth and cardiovascular function. We are using CKD models to understand factors regulating these changes during growth into adulthood.